| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Chong, Vanessa (13)
|
MRLGAC |
4:27.85 |
4:31.22 |
3.37 |
| 2 |
Thomas, Mackenzie (14)
|
MRIA |
4:47.36 |
4:37.95 |
-9.41 |
| 3 |
Rodriguez, Emily M (14)
|
MRLGAC |
4:41.16 |
4:39.41 |
-1.75 |
| 4 |
Egan, Orla M (13)
|
MRLGAC |
4:50.12 |
4:53.95 |
3.83 |
| 5 |
Martinez, Mia N (14)
|
MRLIAC |
5:04.55 |
5:03.72 |
-0.83 |
| 6 |
Heppner, Kathryn C (13)
|
MRLIAC |
5:10.67 |
5:06.77 |
-3.90 |
| 7 |
Hsieh, Kaitlin (14)
|
MRLIAC |
5:06.70 |
5:07.05 |
0.35 |
| 8 |
Piantanida, Carlotta (14)
|
MRLIAC |
5:15.02 |
5:09.29 |
-5.73 |
| 9 |
Brady, Kathryn A (13)
|
MRIA |
5:11.12 |
5:10.37 |
-0.75 |
| 10 |
Nowak, Nicole (14)
|
MRLIAC |
5:18.90 |
5:14.97 |
-3.93 |
| 11 |
Stroub, Mia R (13)
|
MRWISC |
5:46.99 |
5:17.85 |
-29.14 |
| 12 |
Dobrzynski, Tercia Z (13)
|
MRIA |
|
5:20.18 |
- |
| 13 |
Duver, Sophia E (14)
|
MRSS |
5:25.11 |
5:24.12 |
-0.99 |
| 14 |
de Reyna, Jillian L (14)
|
MRLIAC |
5:10.66 |
5:29.55 |
18.89 |
| 15 |
Trieff, Lily S (13)
|
MRSS |
6:25.11 |
6:08.19 |
-16.92 |